Defiance, MO is the gateway to Historic Missouri Wine Country. The Defiance area offers a spectacular destination for weekend retreats, weddings, history exploration, or recreation, and is a wonderful place to live. Located just west of the St. Louis metro area, Defiance is easy to visit and hard not to love. Come explore the Defiance area, and plan your next outing with us!
The Defiance area is rich in history, from the native Ozark Tribe and Daniel Boone to the railroad, river lore, and modern America. There is something to discover for everyone.
There are many important people and events that have made history in and around Defiance. Check out the Daniel Boone Home, the Hays Home, bike the renowned Katy Trail and examine historical markers throughout the area, or follow the river road to take in the unspoiled beauty of the area.
Check our calendar of events for upcoming activities.
Defiance marks the beginning of the Hwy 94 wine trail that extends through Augusta, Dutzow, Marthasville, Hermann, and beyond. Start your adventure with us!
The Defiance area has become the wedding destination of choice for the St. Louis area, hosting hundreds of events annually. Contact one of our outstanding destinations for more details.
There are three wineries within a two-mile radius of Defiance, a brewery, a distillery, and nearly a dozen wineries over the next 15 miles to Dutzow. Each venue offers a spectacular view, award-winning wines, music, and food.
There are numerous lodging options in the area from B&Bs, to vacation and room rentals, each with unique settings, beautiful decor, and wonderful food. Plan a weekend retreat and stay with us!
Hiking, biking, and playing hard in Defiance will leave anyone with a robust hunger. Check out our great eating establishments which offer something for everyone.
Some of the most beautiful and scenic parks in the St. Louis/St. Charles area are found around Defiance. Come visit us for hiking, biking, canoeing, and other activities.